Size:100 μl Price:$ 495 Brand:NewEast Place of Origin:USA Immunogen:
Cat. #: 26462 |
Gene Symbol: BRAF,BRAF1,RAFB1 |
Description: Anti-BRAF(V600M) Mouse Monoclonal Antibody |
Background: BRAF belongs to a family of serine-threonine protein kinases. As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation, differentiation and transcriptional regulation. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been found in cancers. |
Immunogen: A synthetic peptide from the internal region of BRAF which includes the mutation of V600M, human origin. |
Applications: ELISA, IF, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 IF: 1:50-1:100 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes V600M mutant, but not wild type BRAF of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
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