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Yeast Protein Services

Yeast protein expression system is the most economical and efficient expression system among eukaryotic protein expression systems, which combines the advantages of prokaryotic expression system and eukaryotic expression system. Because of its fast growth rate, low culture cost and clear genetic background, it has been widely used in industrial microorganisms. The yeast expression system can correctly process, modify and fold post-translational proteins, so it is often used for the expression of heterologous functional proteins in eukaryotes. Among them, the Pichia pastoris expression system is more widely used. Compared with other systems, it has unique advantages, such as strong promoters FLD1, GAP, AOX1, etc., which can make the expression of heterologous proteins lasting and efficient.

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Mammalian Protein Service

Mammalian cells have become the preferred host cells in the field of biopharmaceuticals. Mammalian cell expression systems can introduce proper protein folding and carry out post-translational modifications, which are essential for full biological activity. The expressed recombinant proteins are closest to the human conformation and have the same biological activity as natural proteins. Heterologous proteins expressed by mammalian cells have the incomparable advantages of specific prokaryotic expression systems and eukaryotic expression systems such as yeast and insect cells in terms of activity, which are closer to natural proteins. Therefore, mammalian cell expression systems have been widely used in the development and production of therapeutic recombinant monoclonal antibody drugs and protein drugs. We has established a mature mammalian protein expression system and purification service platform, providing expression and purification services of mammalian protein expression system to help you quickly obtain high-quality protein.

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E. coli Protein Service

The advantages of E. coli expression systems include easy operation, low cost, high expression, as well as in-depth research on its genetic background and the diversity of vector strain selection, the use of E. coli to overexpress target genes is still the preferred method at present. However, the codon preferences of different species and the cytotoxicity and solubility of expressed products affect the expression of heterologous genes. With our rich experience, We offer multiple fusion/affinity tags to increase the protein solubility, expression levels, and ease of purification.

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Monoclonal antibody customization service

Monoclonal antibodies are a class of antibodies that are produced by hybridoma cells by cell fusion technology and can bind to specific antigenic epitopes. Monoclonal antibodies have the characteristics of batch stability, high specificity and easy large-scale preparation, so they are widely used in biological research, in vitro diagnosis and drug development. According to the different needs of customers, we customize different solutions according to the type, quantity and purity of their antigens; through HAT screening and multiple subcloning screening to ensure 100% purity of cell lines; we use antibody affinity purification to ensure high antibody purity, Whether you use it downstream for diagnostic testing or drug research, its effectiveness is guaranteed.

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Polyclonal Antibody Production Service

Monoclonal antibodies are a class of antibodies that are produced by hybridoma cells by cell fusion technology and can bind to specific antigenic epitopes. Monoclonal antibodies have the characteristics of batch stability, high specificity and easy large-scale preparation, so they are widely used in biological research, in vitro diagnosis and drug development. According to the different needs of customers, we customize different solutions according to the type, quantity and purity of their antigens; through HAT screening and multiple subcloning screening to ensure 100% purity of cell lines; we use antibody affinity purification to ensure high antibody purity, Whether you use it downstream for diagnostic testing or drug research, its effectiveness is guaranteed.

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