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ALK(R1275Q)

26151

Size:100 μl Price:$ 495 Brand:NewEast Place of Origin:USA Immunogen:

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ALK(R1275Q)
Cat. #:   26151
Gene Symbol:  ALK, CD246, NBLST3
Description:   Anti-ALK(R1275Q) Mouse Monoclonal Antibody
Background:   Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers.
Immunogen:   A synthetic peptide from the internal region of ALK which includes the mutation of R1275Q, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:    ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100
Concentration:   0.5 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes ALK(R1275Q), but not wild type ALK protein from vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
Western blot:   Western blot analysis of recombinant ALK(R1275Q) and wild type proteins.  Purified His-tagged ALK(R1275Q) protein (amino acids 1060-1620, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-ALK(R1275Q) mouse monoclonal antibody (Cat. #26151).
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