Size:100 μl Price:$ 219 Brand:NewEast Place of Origin:USA Immunogen:
GRB7 Polyclonal Antibody
Cat. #: 21218 |
Gene Symbol: GRB7 |
Description: Anti-GRB7 Rabbit Polyclonal Antibody |
Background: Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in breast cancers. Grb7 is over-expressed in testicular germ cell tumors, esophageal cancers, and gastric cancers. There are clues that it involved in cell migration and metastatic progression of human esophageal carcinomas. |
Immunogen: A synthetic peptide from the C-terminus of GRB7 protein, human origin. |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:250-1:1000 IHC: 1:50-1:100 |
Concentration: 0.5 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Isotype: IgG |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-GRB7 rabbit polyclonal antibody recognizes GRB7 from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing. |
Western blot: Western blot analysis of GRB7 proteins. Whole-cell lysate of MEF cells was blotted with Anti-GRB7 polyclonal antibody (Cat. #26071). |
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