Size：50 μg
Price：$ 4400
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: 11126 | ||
| Product Name: Human CGRPR-RAMP1 Full Length Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: CALCRL; CRLR; LMPHM8 | ||
| Target: CGRPR | ||
| UNIPROT ID: Q16602 | ||
| Description: Human CGRPR-RAMP1 full length protein-synthetic nanodisc | ||
| Background: The CGRP receptor (CGRPR) is a member of family B G protein coupled receptors (GPCRs), is expressed throughout the trigeminal system, including neurons and endothelial cells. They usually function with accessory proteins such as receptor activity modifying proteins (RAMPs) and Na/H exchange regulatory factors (NHERFs). CGRPR is a heterodimer complex of the calcitonin receptor-like receptor (CRLR) and receptor activity-modifying protein 1 (RAMP1). Therapeutics for migraine treatment are mostly targeting CRLR-RAMP1 protein-protein interaction surfaces, thereby blocking CGRP activity. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The human full length CGRPR protein has a MW of 53.0 kDa | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
|
Select By Alphabet
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Subscribe to our latest email
(+1) 610-945-2007 [email protected] [email protected] 840 First Avenue, Suite 400, King of Prussia, PA 19406
Copyright © 2010 - 2024 NewEast Biosciences | All rights reserved
Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
Add to cart
Buy now
Download
