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CTNNAL1 Rabbit pAb

210192

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S210192
Product Name:   Anti-CTNNAL1 Rabbit Polyclonal Antibody
Synonyms:   ACRP; CLLP; alpha-CATU
UNIPROT ID:   Q9UBT7 (Gene Accession - BC117208 )
Background:    CTNNAL1 (catenin (cadherin-associated protein), alpha-like 1), also known as CLLP or alpha-CATU, is a 734 amino acid cytoplasmic peripheral membrane protein belonging to the vinculin/alpha-catenin family. Expressed at high levels in adrenal gland and present at lower levels in neural tissues, CTNNAL1 may be involved in the regulation of Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor 1 (RhoGEF p115). It is suggested that CTNNAL1 is down-regulated in pancreatic carcinoma undergoing differentiation and apoptosis. Existing as three isforms produced by alternative splicing events, CTNNAL1 may contribute to the wound repair and proliferation of human bronchial epithelial cells (HBEC).
Immunogen:    Fusion protein of human CTNNAL1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 210192(CTNNAL1 Antibody) at a dilution of 1/30(Cytoplasm and Cell membrane).

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer tissue using 210192(Anti-CTNNAL1 Antibody) at a dilution of 1/30.
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