Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S222294 | ||||
| Product Name: Anti-RBFOX1 Rabbit Polyclonal Antibody | ||||
| Synonyms: 2BP1; FOX1; A2BP1; FOX-1; HRNBP1 | ||||
| UNIPROT ID: Q9NWB1 (Gene Accession - NP_001135805 ) | ||||
| Background: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. | ||||
| Immunogen: Synthetic peptide of human RBFOX1 | ||||
| Applications: ELISA, IHC | ||||
| Recommended Dilutions: IHC: 40-200; ELISA: 5000-10000 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Polyclonal | ||||
| Isotype: Immunogen-specific rabbit IgG | ||||
| Purification: Antigen affinity purification | ||||
| Species Reactivity: Human, Mouse | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
| Research Areas: Epigenetics and Nuclear Signaling, Neuroscience, Developmental Biology | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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