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SIRT6 (6C9) Mouse mAb

261411

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261411
Product Name:   Anti-SIRT6 (6C9) Mouse Monoclonal Antibody
Synonyms:   2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2
UNIPROT ID:   Q8N6T7
Background:    The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.
Immunogen:    Purified recombinant human SIRT6 protein expressed in E.coli.
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    6C9-D10-D3
MW:    Calculated MW: 39 kDa; Observed MW: 42 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat,Monkey
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    EpigeneticsyyyyyHistone Acetylation
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of SIRT6 (6C9) in Hela using SIRT6 antibody.

Western blot analysis of SIRT6 (6C9) in Jurkat, MCF-7, HCT116, K562, COS7, C2C12, 3T3 and Hela lysates using SIRT6 antibody.

Immunoprecipitation analysis of SIRT6 (6C9) in Hela lysates using SIRT6 antibody.
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