Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N261420 | ||||
| Product Name: Anti-DNA PKcs (8D3) Mouse Monoclonal Antibody | ||||
| Synonyms: PRKDC; HYRC; HYRC1; DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; p460 | ||||
| UNIPROT ID: P78527 | ||||
| Background: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. | ||||
| Immunogen: Purified recombinant human DNA-PKcs protein fragments expressed in E.coli | ||||
| Applications: WB,ICC/IF,IP | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 | ||||
| Host Species: Mouse | ||||
| Clonality: Mouse Monoclonal | ||||
| Clone ID: 8D3-B12-F11 | ||||
| MW: Calculated MW: 469 kDa; Observed MW: 450 kDa | ||||
| Isotype: IgG2b | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human | ||||
| Conjugation: Unconjugated | ||||
| Modification: Unmodified | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: Epigenetics and Nuclear Signaling | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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