Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N261438 |
| Product Name: Anti-Ku70 (6H10) Mouse Monoclonal Antibody |
| Synonyms: XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box- |
| UNIPROT ID: P12956 |
| Background: It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together. |
| Immunogen: Purified recombinant human Ku70 protein fragments expressed in E.coli. |
| Applications: WB,ICC/IF |
| Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 |
| Host Species: Mouse |
| Clonality: Mouse Monoclonal |
| Clone ID: 6H10-E9-G7 |
| MW: Calculated MW: 70 kDa; Observed MW: 70 kDa |
| Isotype: IgG2b |
| Purification: Affinity Purified |
| Species Reactivity: Human |
| Conjugation: Unconjugated |
| Modification: Unmodified |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Research Areas: Epigenetics and Nuclear Signaling |
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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