Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261445 |
Product Name: Anti-EGFR (D115D6) Mouse Monoclonal Antibody |
Synonyms: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 |
UNIPROT ID: P00533 |
Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. |
Immunogen: Purified recombinant human EGFR protein fragments expressed in E.coli. |
Applications: WB,ELISA |
Recommended Dilutions: WB: 1/500-1/1000 ELISA: 1/10000 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: D11-5D6-2F3 |
MW: Calculated MW: 134 kDa; Observed MW: 130-180 kDa |
Isotype: IgG1 |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Signal Transduction |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase