Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N263383 |
Product Name: Anti-IL-1 Receptor Accessory Protein Rabbit Monoclonal Antibody |
Synonyms: IL-1 Receptor Accessory Protein; IL1R3; C3orf13; IL-1RAcP |
UNIPROT ID: Q9NPH3 |
Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. |
Immunogen: Recombinant protein of human IL-1RAcP |
Applications: WB,IP |
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R05-3B8 |
MW: Calculated MW: 65 kDa; Observed MW: 78 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Immunology |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of IL-1RAcP in HL-60, U251, U87-MG lysates using IL-1 Receptor Accessory Protein antibody. |
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