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Phospholipase C gamma 1 Rabbit mAb

263492

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263492
Product Name:   Anti-Phospholipase C gamma 1 Rabbit Monoclonal Antibody
Synonyms:   PLCG1; PLC1; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1
UNIPROT ID:   P19174
Background:    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.
Immunogen:    A synthetic peptide of human Phospholipase C gamma 1/PLC-gamma-1
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-6B4
MW:    Calculated MW: 149 kDa; Observed MW: 149 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-lipase C gamma 1/PLCgamma1 in U2OS, C6 lysates using Phospho-lipase C gamma 1/PLCgamma1 antibody.

Immunocytochemistry analysis of Phospho-lipase C gamma 1 (green) in Hela using Phospho-lipase C gamma 1 antibody,and DAPI(blue).
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