SNAP25 Rabbit mAb

263554

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263554

Product Name: Anti-SNAP25 Rabbit Monoclonal Antibody

Synonyms: Synaptosomal-associated protein 25; SNAP-25; Super protein; SUP; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP

UNIPROT ID: P60880

Background: SNAP25 forms a core complex with the SNARE proteins syntaxin and synaptobrevin to mediate synaptic vesicle fusion with the plasma membrane during Ca2+-dependent exocytosis. This complex is responsible for exocytosis of the neurotransmitter γ-aminobutyric acid (GABA). Neurotransmitter release is inhibited by proteolysis of SNAP25 by botulinum toxins A and E. SNAP25 plays a secondary role as a Q-SNARE involved in endosome fusion; the protein is associated with genetic susceptibility to attention-deficit hyperactivity disorder (ADHD).

Immunogen: A synthetic peptide of human SNAP25

Applications: WB,ICC/IF,IP

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R07-1D7

MW: Calculated MW: 23 kDa; Observed MW: 23 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Mouse,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: NeuroscienceyyyyySNAP25

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of SNAP25 in HL-60, C6 lysates using SNAP25 antibody	Immunocytochemistry analysis of SNAP25 (green) in Hela using SNAP25 antibody,and DAPI(blue).
Western blot analysis of SNAP25 in mouse brain lysates using SNAP25 antibody.

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