IL1A(4G2) IgG1 Chimeric mAb

28569

Size：100 µg Price：$ 1600 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 28569

Product Name: Anti-IL1A(4G2) IgG1 Chimeric Monoclonal Antibody

Synonyms: IL-1 alpha;IL-1A;IL1;IL1-ALPHA;IL1F1

Description: Anti-IL1A antibody(4G2) IgG1 Chimeric Monoclonal Antibody

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]

Applications: Flow Cyt

Recommended Dilutions: Flow Cyt 1/100

Host Species: Rabbit

Isotype: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Species Reactivity: Human IL1A

Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IL1A (4G2) mAb on Expi293 cells transfected with human IL1A (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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