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Human GPR132 Protein

12279

Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12279
Product Name:   Human GPR132 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   G2A
Target:    GPR132
UNIPROT ID:    Q9UNW8
Description:    Recombinant human GPR132 Protein with C-terminal human Fc tag
Background:     This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 30.9 kDa after removal of the signal peptide. The apparent molecular mass of GPR132-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    GPR132(Met1-Leu45) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GPR132 Protein, hFc Tag on SDS-PAGE under reducing condition.
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