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Human F2RL3 Protein

12280

Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12280
Product Name:   Human F2RL3 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   PAR4
Target:    F2RL3
UNIPROT ID:    Q96RI0
Description:    Recombinant human F2RL3 Protein with C-terminal human Fc tag
Background:     This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 29.5 kDa after removal of the signal peptide. The apparent molecular mass of F2RL3-hFc is approximately 25-55 kDa due to glycosylation.
Molecular Characterization:    F2RL3(Gly48-Arg78) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human F2RL3 Protein, hFc Tag on SDS-PAGE under reducing condition.
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