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Rac1 mAb

26005

Size:100 μl Price:$ 239 Brand:NewEast Place of Origin:USA Immunogen:

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Rac1 Monoclonal Antibody
Cat. #:  26005
Gene Symbol:  RAC1
Description:   Anti-Rac1 Mouse Monoclonal Antibody
Background:   Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. In mammals, there are three Rac genes: Rac1, Rac2 and Rac3. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
Immunogen:   Recombinant full length protein of Rac1
Applications:   ELISA, WB, IHC
Recommended Dilutions:   ELISA 1:1000-1:5000 WB 1:1000-1:2000
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Rac1 antibody recognizes Rac1 from vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing
Western blot:   image.png Western blot analysis of Rac1 proteins. MEF whole-cell lysate was used for western blots. The monoclonal Anti-Rac1 antibody was pre-incubated without (lane 1) or with (lane 2) the antigen protein (Rac1) to show the specificity .
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