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ALK(D1225N)

26290

Size:100 μl Price:$ 495 Brand:NewEast Place of Origin:USA Immunogen:

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ALK(D1225N)

Cat. #:  26290
Gene Symbol:  ALK, CD246, NBLST3
Description:   Anti-ALK(D1225N) Mouse Monoclonal Antibody
Background:   Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers.
Immunogen:   A synthetic peptide from the internal region of ALK which includes the mutation of D1225N, human origin.
Applications:   ELISA, WB
Recommended Dilutions:   
ELISA: 1:1000-1:5000
WB: 1:500-1:2000
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes D1225N mutant, but not wild type ALK of vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

Western blot analysis of recombinant ALK(D1225N) and wild type proteins. Purified His-tagged ALK(D1225N) protein (1060-1620aa, 68KD, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-ALK(D1225N) monoclonal antibody (Cat. #26290).

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