Size：100 μl
Price：$ 495
Brand：NewEast 
Place of Origin：USA
Immunogen：
Gαq(Q209R)
| Cat. #: 26330 |
| Gene Symbol: GNAQ, CMC1, G-ALPHA-q, GAQ, SWS |
| Description: Anti-GNAQ(Q209R) Mouse Monoclonal Antibody |
| Background: GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. |
| Immunogen: A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209R, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes Q209R mutant, but not wild type GNAQ of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Western blot analysis of recombinant GNAQ(Q209R) and wild type proteins. Purified His-tagged GNAQ(Q209R) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-GNAQ(Q209R) monoclonal antibody (Cat. #26330). Immunofluorescence:
Immunofluorescence of cells expressing GNAQ proteins with Anti-GNAQ(Q209R) antibody. HEK293T cells were transfected with pCDNA3-GFP-GNAQ(Q209R) plasmid, pCDNA3-GFP-GNAQ (WT) plasmid, pCDNA3-GFP-GNAQ (Q209L) plasmid or pCDNA3-GFP-GNAQ (Q209P) plasmid, then fixed and stained with Anti-GNAQ(Q209R) monoclonal antibody (Cat. #26330). |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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