Size：100 μl
Price：$ 239
Brand：NewEast 
Place of Origin：USA
Immunogen：
BRCA2(1475-1748)
| Cat. #: 26364-2 |
| Gene Symbol: BRCA2, BRCC2, FAD1,FCD, BROVCA2, PNCA2 |
| Description: Anti-BRCA2(1475-1748) Mouse Monoclonal Antibody |
| Background: BRCA2 is a human tumor suppressor gene. Its protein, also called by the synonym breast cancer type 2 susceptibility protein, is responsible for repairing DNA. Mutations of BRCA2 can cause an increased risk of breast cancer. In addition to breast cancer in men and women, mutations in BRCA2 also lead to an increased risk of ovarian, Fallopian tube, prostate, and pancreatic cancers, as well as malignant melanoma. |
| Immunogen: Purified BRCA2(1475-1748) protein, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes BRCA2(1475-1748) of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
| Western blot: Western blot analysis of recombinant BRCA2 proteins. Purified His-tagged BRCA2 (352-643) protein (lane1), His-tagged BRCA2(1475-1748) protein(lane2), His-tagged BRCA2 (2213-2543) protein(lane3) and His-tagged BRCA2 (2793-3030) protein (lane4) were blotted with Anti-BRCA2(1475-1748) monoclonal antibody (Cat. # 26364-2). Immunofluorescence: HEK293T cells was transfected with pCDNA3-GFP-BRCA2(1475-1748) plasmid, then fixed and stained with Anti-BRCA2(1475-1748) monoclonal antibody (Cat. # 26364-2). |
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