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CD123 mAb (Talacotuzumab)

28012

Size:100 μg Price:$ 199 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   28012
Product Name:   Anti-CD123 (Talacotuzumab) Monoclonal Antibody
Synonyms:   CD123;IL3R;IL3RA
Description:    Anti-CD123 (talacotuzumab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Humanized
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD123
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human CD123, hFc-His tagged protein (11131) can bind Anti-CD123 Neutralizing antibody in a linear range of 0.98-26.70 ng/ml. In order to specifically detect 28012, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 2. HEK293 cell line transfected with irrelevant protein  (B) and human CD123  (A) were surface stained with anti-CD123 neutralizing antibody 1µg/ml (talacotuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
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