Size:100 μg Price:$ 445 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 28496 | ||
Product Name: Anti-IL6R(DM152) Rabbit Monoclonal Antibody | ||
Synonyms: CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ | ||
Description: Anti-IL6R antibody(DM152) Rabbit Monoclonal Antibody | ||
Background: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST:GP130:IL6-beta); a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases; such as multiple myeloma; autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. | ||
Applications: ELISA; Flow Cyt | ||
Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
Host Species: Rabbit | ||
Isotype: Rabbit IgG | ||
Purification: Purified from cell culture supernatant by affinity chromatography | ||
Species Reactivity: Human IL6R | ||
Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase