Size：100 μg
Price：$ 445
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: 28487 | ||
| Product Name: Anti-BAFF-R(DM143) Rabbit Monoclonal Antibody | ||
| Synonyms: BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin | ||
| Description: Anti-BAFF-R antibody(DM143) Rabbit Monoclonal Antibody | ||
| Background: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. | ||
| Applications: ELISA; Flow Cyt | ||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
| Host Species: Rabbit | ||
| Isotype: Rabbit IgG | ||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||
| Species Reactivity: Human BAFF-R | ||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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