Size：100 μg
Price：$ 445
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: 28472 |
| Product Name: Anti-BAFF-R(DM127) Rabbit Monoclonal Antibody |
| Synonyms: BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin |
| Description: Anti-BAFF-R antibody(DM127) Rabbit Monoclonal Antibody |
| Background: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva |
| Applications: Flow Cyt |
| Recommended Dilutions: Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit IgG |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human BAFF-R |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. Flow cytometry analysis with Anti-BAFF-R (DM127) on Expi293 cells transfected with human BAFF-R (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram). |
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