Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S214897 | ||
| Product Name: Anti-IL6ST Rabbit Polyclonal Antibody | ||
| Synonyms: CD130; GP130; CDW130; IL-6RB | ||
| UNIPROT ID: P40189 (Gene Accession - NP_002175 ) | ||
| Background: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. | ||
| Immunogen: Synthetic peptide of human IL6ST | ||
| Applications: ELISA, IHC | ||
| Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Polyclonal | ||
| Isotype: Immunogen-specific rabbit IgG | ||
| Purification: Antigen affinity purification | ||
| Species Reactivity: Human, Mouse, Rat | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
| Research Areas: Signal Transduction, Cancer, Cardiovascular, Immunology | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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