Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: S217262 | ||||||
Product Name: Anti-CD27 Rabbit Polyclonal Antibody | ||||||
Synonyms: T14; S152; Tp55; TNFRSF7; S152. LPFS2 | ||||||
UNIPROT ID: P26842 (Gene Accession - BC012160 ) | ||||||
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. | ||||||
Immunogen: Fusion protein of human CD27 | ||||||
Applications: ELISA, WB, IHC | ||||||
Recommended Dilutions: IHC: 50-200;WB: 1000-5000;ELISA: 2000-5000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Isotype: Immunogen-specific rabbit IgG | ||||||
Purification: Antigen affinity purification | ||||||
Species Reactivity: Human | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
Research Areas: Cancer, Immunology, Stem Cells | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase