Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S217265 | ||||
| Product Name: Anti-CD33 Rabbit Polyclonal Antibody | ||||
| Synonyms: p67; SIGLEC3; SIGLEC-3 | ||||
| UNIPROT ID: P20138 (Gene Accession - BC028152 ) | ||||
| Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). | ||||
| Immunogen: Fusion protein of human CD33 | ||||
| Applications: ELISA, WB, IHC | ||||
| Recommended Dilutions: IHC: 50-100;WB: 500-2000;ELISA: 5000-10000 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Polyclonal | ||||
| Isotype: Immunogen-specific rabbit IgG | ||||
| Purification: Antigen affinity purification | ||||
| Species Reactivity: Human, Mouse | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
| Research Areas: Immunology, Stem Cells | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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