CTLA4 Rabbit pAb

219723

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S219723

Product Name: Anti-CTLA4 Rabbit Polyclonal Antibody

Synonyms: CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3

UNIPROT ID: P16410 (Gene Accession - NP_005205 )

Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Immunogen: Synthetic peptide of human CTLA4

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Immunology, Stem Cells

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human prostate cancer tissue using 219723(CTLA4 Antibody) at a dilution of 1/50(Cytoplasm and Cell membrane).

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Product Categories

CTLA4 Rabbit pAb

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