Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S219864 | ||
| Product Name: Anti-IL2RA Rabbit Polyclonal Antibody | ||
| Synonyms: p55; CD25; IL2R; IMD41; TCGFR; IDDM10 | ||
| UNIPROT ID: P01589 (Gene Accession - NP_000408 ) | ||
| Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] | ||
| Immunogen: Synthetic peptide of human IL2RA | ||
| Applications: ELISA, IHC | ||
| Recommended Dilutions: IHC: 50-200; ELISA: 5000-10000 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Polyclonal | ||
| Isotype: Immunogen-specific rabbit IgG | ||
| Purification: Antigen affinity purification | ||
| Species Reactivity: Human, Mouse, Rat | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
| Research Areas: Immunology, Neuroscience, Cancer | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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