Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N225405 |
| Product Name: Anti-SOCS1 Rabbit pAb |
| Synonyms: SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3 |
| UNIPROT ID: O15524 |
| Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
| Immunogen: The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98 |
| Applications: ICC/IF,WB,IHC-F,IHC-P,ELISA |
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000 |
| Host Species: Rabbit |
| Clonality: Rabbit Polyclonal |
| Clone ID: - |
| MW: Calculated MW: 24 kDa; Observed MW: 38 kDa |
| Isotype: IgG |
| Purification: Affinity Purified |
| Species Reactivity: Human,Mouse,Rat |
| Conjugation: Unconjugated |
| Modification: Unmodified |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Research Areas: Signal Transduction |
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of SOCS1 in Jurkat lysates using SOCS1 antibody. |
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