Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N225831 |
Product Name: Anti-SNAP25 Rabbit pAb |
Synonyms: Synaptosomal-associated protein 25; SNAP-25; Super protein; SUP; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP |
UNIPROT ID: P60880 |
Background: SNAP25 forms a core complex with the SNARE proteins syntaxin and synaptobrevin to mediate synaptic vesicle fusion with the plasma membrane during Ca2+-dependent exocytosis. This complex is responsible for exocytosis of the neurotransmitter γ-aminobutyric acid (GABA). Neurotransmitter release is inhibited by proteolysis of SNAP25 by botulinum toxins A and E. SNAP25 plays a secondary role as a Q-SNARE involved in endosome fusion; the protein is associated with genetic susceptibility to attention-deficit hyperactivity disorder (ADHD). |
Immunogen: A synthesized peptide derived from human SNAP25 |
Applications: WB,ICC/IF,IP |
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Clone ID: - |
MW: Calculated MW: 23 kDa; Observed MW: 23 kDa |
Isotype: IgG |
Purification: Affinity Chromatography |
Species Reactivity: Human,Mouse,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: NeuroscienceyyyyySNAP25 |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of SNAP25 in SH-SY5Y lysates using SNAP25 antibody. |
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